HMB (ß-Hydroxy ß-Methylbutyrate) is a metabolite of the amino acid Leucine. It’s needed by the body to protect and repair muscle tissue. Regular consumption of HMB slows down protein breakdown and improves protein synthesis. In athletes who engage in intense weight and resistance training this has numerous benefits: lean muscle gains, greater strength output, faster recovery and overall better response to training. It helps minimizing muscle breakdown during training and directly supports muscle tissue repair, one serving of HMB 1000 should always be taken prior to working out. The more intense you train, the greater the benefits of HMB will be.
In humans, most of betaine's purported benefits derive from its role as a methyl donor. A methyl donor is any molecule that can transfer a methyl group, which is a carbon atom attached to three hydrogen atoms, to another molecule. Many important biochemical processes in the body rely on methylation.The most critical reaction where betaine performs this function is in the methylation of the amino acid homocysteine to form methionine. Methionine is important in the body's internal synthesis of creatine. So one way that betaine may boost muscle strength and size is by increasing creatine production in the body.*Methionine also plays an important role in muscle protein synthesis, and specifically the process known as "translation." By having more methionine available for this process, protein synthesis is ramped up, and therefore so is the potential for muscle growth and strength gains.
Betaine may also has the beneficial effect of supporting healthy homocysteine levels.* High homocysteine levels have been shown to impair insulin signaling, which can interfere with muscle growth and fat loss.
And finally, betaine supplementation has also been suggested to raise levels of S-adenosylmethionine, also known as SAMe. Having healthy levels of SAMe may support positive mood, promote liver health, and aid joint recovery.*